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November 11, 2022
Clinical Outcomes
Article / Publication

The Wireless Innovation for Seniors with Diabetes Mellitus (WISDM) randomized clinical trial (RCT) featured a 26-week phase comparing real-time continuous glucose monitoring (RT-CGM) with blood glucose monitoring (BGM) in 203 adults aged ≥60 years with type 1 diabetes (T1D). Of the 198 participants who completed the RCT, 98% of RT-CGM group participants continued (CGM-CGM cohort) and 98% of BGM group participants crossed over to CGM (BGM-CGM cohort) for an additional 26 weeks. In the BGM-CGM cohort, median time <70 mg/dL decreased from 3.9% to 1.9% (P<0.001), TIR increased from 56% to 60% (P=0.006) and HbA1c decreased from 7.5% to 7.3% (P=0.025). Severe hypoglycemic events were reported for 9 participants while using BGM during the RCT and for only 2 participants during the extension phase with RT-CGM (P=0.02), indicating a sustained benefit of hypoglycemia avoidance in older adults out to 12 months.

Miller KM, et al. Benefit of Continuous Glucose Monitoring in Reducing Hypoglycemia Is Sustained Through 12 Months of Use Among Older Adults with Type 1 Diabetes. Diabetes Technol Ther. 2022;24(6):424-434.

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